SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells

In this report, we show that malignant pleural mesothelioma (MPM) patients whose tumors express high levels of AKT1 exhibit a significantly worse prognosis, whereas no significant correlation with AKT3 expression is observed. We provide data that establish a phosphorylation independent role of AKT1...

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Detalles Bibliográficos
Autores principales: Pinton, Giulia, Zonca, Sara, Manente, Arcangela G., Cavaletto, Maria, Borroni, Ester, Daga, Antonio, Jithesh, Puthen V., Fennell, Dean, Nilsson, Stefan, Moro, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924721/
https://www.ncbi.nlm.nih.gov/pubmed/26885609
http://dx.doi.org/10.18632/oncotarget.7321

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