MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells

LIN28A aberrant expression contributes to the development of human malignancies. However, the LIN28A expression profile remains to be clarified. Herein, we report that LIN28A expression is directly associated with the methylation status of its two CpG island sites in pancreatic cancer cells. First,...

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Detalles Bibliográficos
Autores principales: Xu, Min, Bian, Shihui, Li, Jie, He, Junbo, Chen, Hui, Ge, Lu, Jiao, Zhijun, Zhang, Youli, Peng, Wanxin, Du, Fengyi, Mo, Yinyuan, Gong, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924729/
https://www.ncbi.nlm.nih.gov/pubmed/26910839
http://dx.doi.org/10.18632/oncotarget.7507

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