Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

Meningiomas are frequent central nervous system tumors. Although most meningiomas are benign (WHO grade I) and curable by surgery, WHO grade II and III tumors remain therapeutically challenging due to frequent recurrence. Interestingly, relapse also occurs in some WHO grade I meningiomas. Hence, we...

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Detalles Bibliográficos
Autores principales: Schmidt, Melissa, Mock, Andreas, Jungk, Christine, Sahm, Felix, Ull, Anna Theresa, Warta, Rolf, Lamszus, Katrin, Gousias, Konstantinos, Ketter, Ralf, Roesch, Saskia, Rapp, Carmen, Schefzyk, Sebastian, Urbschat, Steffi, Lahrmann, Bernd, Kessler, Almuth F., Löhr, Mario, Senft, Christian, Grabe, Niels, Reuss, David, Beckhove, Philipp, Westphal, Manfred, von Deimling, Andreas, Unterberg, Andreas, Simon, Matthias, Herold-Mende, Christel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924735/
https://www.ncbi.nlm.nih.gov/pubmed/26894859
http://dx.doi.org/10.18632/oncotarget.7396

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