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Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia

Hypoxia leads to reactive oxygen species (ROS) imbalance, which is proposed to associate with drug resistance and oncogenesis. Inhibition of enzymes of antioxidant balancing system in tumor cells was shown to reduce chemoresistance under hypoxia. However, the underlying mechanism remains unknown. Th...

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Detalles Bibliográficos
Autores principales:	Syu, Jhih-Pu, Chi, Jen-Tsan, Kung, Hsiu-Ni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924742/ https://www.ncbi.nlm.nih.gov/pubmed/26894974 http://dx.doi.org/10.18632/oncotarget.7406

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