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MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer

Mitochondrial pyruvate carrier 1 (MPC1) and MPC 2 form a transporter complex in cells to control pyruvate transportation into mitochondria. Reduced expression of MPC1 disrupts the transporter function, induces metabolic shift to increase glycolysis, and thus plays important roles in several diseases...

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Detalles Bibliográficos
Autores principales: Wang, Leiming, Xu, Mafei, Qin, Jun, Lin, Shih-Chieh, Lee, Hui-Ju, Tsai, Sophia Y., Tsai, Ming-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924743/
https://www.ncbi.nlm.nih.gov/pubmed/26895100
http://dx.doi.org/10.18632/oncotarget.7405