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A novel miR-34a target, protein kinase D1, stimulates cancer stemness and drug resistance through GSK3/β-catenin signaling in breast cancer

One of the properties of human breast cancer cells is cancer stemness, which is characterized by self-renewal capability and drug resistance. Protein kinase D1 (PRKD1) functions as a key regulator of many cellular processes and is downregulated in invasive breast cancer cells. In this study, we foun...

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Detalles Bibliográficos
Autores principales: Kim, Do Yeon, Park, Eun Young, Chang, EunSun, Kang, Hyeok-Gu, Koo, Yoonjin, Lee, Eun Ji, Ko, Je Yeong, Kong, Hyun Kyung, Chun, Kyung-Hee, Park, Jong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924752/
https://www.ncbi.nlm.nih.gov/pubmed/26895471
http://dx.doi.org/10.18632/oncotarget.7443