Cargando…

A novel miR-34a target, protein kinase D1, stimulates cancer stemness and drug resistance through GSK3/β-catenin signaling in breast cancer

One of the properties of human breast cancer cells is cancer stemness, which is characterized by self-renewal capability and drug resistance. Protein kinase D1 (PRKD1) functions as a key regulator of many cellular processes and is downregulated in invasive breast cancer cells. In this study, we foun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Do Yeon, Park, Eun Young, Chang, EunSun, Kang, Hyeok-Gu, Koo, Yoonjin, Lee, Eun Ji, Ko, Je Yeong, Kong, Hyun Kyung, Chun, Kyung-Hee, Park, Jong Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924752/ https://www.ncbi.nlm.nih.gov/pubmed/26895471 http://dx.doi.org/10.18632/oncotarget.7443

Ejemplares similares

Interplay Between Primary Cilia and Autophagy and Its Controversial Roles in Cancer
por: Ko, Je Yeong, et al.
Publicado: (2019)

TRIB2 Stimulates Cancer Stem-Like Properties through Activating the AKT-GSK3β-β-Catenin Signaling Axis
por: Kim, Dae Kyoung, et al.
Publicado: (2021)

Autophagy inhibits cancer stemness in triple‐negative breast cancer via miR‐181a‐mediated regulation of ATG5 and/or ATG2B
por: Park, Jee Won, et al.
Publicado: (2022)

Long non-coding RNAs: key regulators of liver and kidney fibrogenesis
por: Han, Su-hyang, et al.
Publicado: (2023)

The Significance of miR-34a Expression in Endometrial Carcinogenesis: Correlation With Expression of p16 and Ki-67 Proteins in Endometrial Cancers
por: Choi, Yoon Sung, et al.
Publicado: (2015)

α-Actinin-4 Promotes the Progression of Prostate Cancer Through the Akt/GSK-3β/β-Catenin Signaling Pathway
por: Park, Sungyeon, et al.
Publicado: (2020)

Targeting phosphomevalonate kinase enhances radiosensitivity via ubiquitination of the replication protein A1 in lung cancer cells
por: Park, Seok Soon, et al.
Publicado: (2023)

Reduced miR-371b-5p expression drives tumor progression via CSDE1/RAC1 regulation in triple-negative breast cancer
por: Kim, Yesol, et al.
Publicado: (2022)

Discovering Breast Cancer Biomarkers Candidates through mRNA Expression Analysis Based on The Cancer Genome Atlas Database
por: Kim, Dong Hyeok, et al.
Publicado: (2022)

Inhibition of β-Catenin to Overcome Endocrine Resistance in Tamoxifen-Resistant Breast Cancer Cell Line
por: Won, Hye Sung, et al.
Publicado: (2016)

Inhibition of PI3K/Akt signaling suppresses epithelial-to-mesenchymal transition in hepatocellular carcinoma through the Snail/GSK-3/beta-catenin pathway
por: Lee, Seulki, et al.
Publicado: (2020)

Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma
por: Kong, Hyun Kyung, et al.
Publicado: (2016)

Additional lesions seen in magnetic resonance imaging of breast cancer patients: the role of second-look ultrasound and imaging-guided interventions
por: Park, So Yoon, et al.
Publicado: (2019)

Antagonist Effects of Veratric Acid against UVB-Induced Cell Damages
por: Shin, Seoung Woo, et al.
Publicado: (2013)

The GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of β-catenin, a GSK3 substrate, in human glioblastoma cells
por: Abdul, Ata ur Rahman Mohammed, et al.
Publicado: (2017)

Reduced expression of TAZ inhibits primary cilium formation in renal glomeruli
por: Jun, Jae Hee, et al.
Publicado: (2022)

Phosphorylation of β‐catenin Ser60 by polo‐like kinase 1 drives the completion of cytokinesis
por: Yu, Ji Eun, et al.
Publicado: (2021)

Deficiency of calpain-6 inhibits primary ciliogenesis
por: Kim, Bo Hye, et al.
Publicado: (2019)

Relationship Between Urinary 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol and Lung Cancer Risk in the General Population: A Community-Based Prospective Cohort Study
por: Park, Eun Young, et al.
Publicado: (2021)

Perspective on Cancer Therapeutics Utilizing Analysis of Circulating Tumor Cells
por: Jeong, Keun-Yeong, et al.
Publicado: (2018)

GSK-3α Is a Novel Target of CREB and CREB-GSK-3α Signaling Participates in Cell Viability in Lung Cancer
por: Park, Sin-Aye, et al.
Publicado: (2016)

MiR-34a and miR-34b/c have distinct effects on the suppression of lung adenocarcinomas
por: Kim, Jeong Seon, et al.
Publicado: (2019)

Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer
por: Kang, Hyeon Woong, et al.
Publicado: (2023)

Diagnostic performance of abbreviated breast MRI for screening of women with previously treated breast cancer
por: Kwon, Mi-ri, et al.
Publicado: (2020)

The effect of breast cancer surgery on spine alignment: Whole-spine radiograph analysis
por: Nam, Kyung Eun, et al.
Publicado: (2022)

Favorable prognosis in colorectal cancer patients with co-expression of c-MYC and ß-catenin
por: Lee, Kyu Sang, et al.
Publicado: (2016)

Identification of miR-143-3p as a diagnostic biomarker in gastric cancer
por: Ju, Yeongdon, et al.
Publicado: (2023)

Methyltransferases in the Pathogenesis of Keratinocyte Cancers
por: Ko, Eun Kyung, et al.
Publicado: (2021)

20S-Protopanaxadiol, an aglycosylated ginsenoside metabolite, induces hepatic stellate cell apoptosis through liver kinase B1–AMP-activated protein kinase activation
por: Park, Sang Mi, et al.
Publicado: (2017)

Analysis of factors influencing the degree of detectability on diffusion-weighted MRI and diffusion background signals in patients with invasive breast cancer
por: Hahn, Soo Yeon, et al.
Publicado: (2016)

Ductal carcinoma in situ: a risk prediction model for the underestimation of invasive breast cancer
por: Park, Ko Woon, et al.
Publicado: (2022)

Regulation of Microglia and Macrophage Polarization via Apoptosis Signal-Regulating Kinase 1 Silencing after Ischemic/Hypoxic Injury
por: Cheon, So Yeong, et al.
Publicado: (2017)

GSK3B induces autophagy by phosphorylating ULK1
por: Ryu, Hye Young, et al.
Publicado: (2021)

Profiling of miRNAs and target genes related to cystogenesis in ADPKD mouse models
por: Woo, Yu Mi, et al.
Publicado: (2017)

RPL17 Promotes Colorectal Cancer Proliferation and Stemness through ERK and NEK2/β-catenin Signaling Pathways
por: Ko, Min Ji, et al.
Publicado: (2022)

KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer
por: Cho, Yong-Hee, et al.
Publicado: (2016)

7-HYB, a Phenolic Compound Isolated from Myristica fragrans Houtt Increases Cell Migration, Osteoblast Differentiation, and Mineralization through BMP2 and β-catenin Signaling
por: Park, Kyung-Ran, et al.
Publicado: (2020)

5-Bromo-3,4-dihydroxybenzaldehyde Promotes Hair Growth through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells
por: Kang, Jung-Il, et al.
Publicado: (2022)

Role of LAMMER Kinase in Cell Wall Biogenesis during Vegetative Growth of Aspergillus nidulans
por: Choi, Yu Kyung, et al.
Publicado: (2014)

Heregulin-β1 Activates NF-E2-related Factor 2 and Induces Manganese Superoxide Dismutase Expression in Human Breast Cancer Cells via Protein Kinase B and Extracellular Signal-regulated Protein Kinase Signaling Pathways
por: Park, Ji-Young, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_v6j8rthqos5d3m0srdccdheln4