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Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells

Accumulating data indicates that chromosome instability (CIN) common to cancer cells can be used as a target for cancer therapy. At present the rate of chromosome mis-segregation is quantified by laborious techniques such as coupling clonal cell analysis with karyotyping or fluorescence in situ hybr...

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Detalles Bibliográficos
Autores principales:	Kim, Jung-Hyun, Lee, Hee-Sheung, Lee, Nicholas C. O., Goncharov, Nikolay V., Kumeiko, Vadim, Masumoto, Hiroshi, Earnshaw, William C., Kouprina, Natalay, Larionov, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924756/ https://www.ncbi.nlm.nih.gov/pubmed/26943579 http://dx.doi.org/10.18632/oncotarget.7854

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