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P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth
De novo fatty acid (FA) synthesis is required for prostate cancer (PCa) survival and progression. As a key enzyme for FA synthesis fatty acid synthase (FASN) is often overexpressed in human prostate cancers and its expression correlates with worse prognosis and poor survival. P300 is an acetyltransf...
Autores principales: | Gang, Xiaokun, Yang, Yinhui, Zhong, Jian, Jiang, Kui, Pan, Yunqian, Karnes, R. Jeffrey, Zhang, Jun, Xu, Wanhai, Wang, Guixia, Huang, Haojie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924775/ https://www.ncbi.nlm.nih.gov/pubmed/26934656 http://dx.doi.org/10.18632/oncotarget.7715 |
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