Two Escape Mechanisms of Influenza A Virus to a Broadly Neutralizing Stalk-Binding Antibody

Broadly neutralizing antibodies targeting the stalk region of influenza A virus (IAV) hemagglutinin (HA) are effective in blocking virus infection both in vitro and in vivo. The highly conserved epitopes recognized by these antibodies are critical for the membrane fusion function of HA and therefore...

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Detalles Bibliográficos
Autores principales: Chai, Ning, Swem, Lee R., Reichelt, Mike, Chen-Harris, Haiyin, Luis, Elizabeth, Park, Summer, Fouts, Ashley, Lupardus, Patrick, Wu, Thomas D., Li, Olga, McBride, Jacqueline, Lawrence, Michael, Xu, Min, Tan, Man-Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924800/
https://www.ncbi.nlm.nih.gov/pubmed/27351973
http://dx.doi.org/10.1371/journal.ppat.1005702

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