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Thromboxane A(2) Regulates CXCL1 and CXCL8 Chemokine Expression in the Nasal Mucosa–Derived Fibroblasts of Chronic Rhinosinusitis Patients

BACKGROUND: Chronic rhinosinusitis without nasal polyps (CRSsNP) is a common chronic disease and the etiology remains unclear. Thromboxane A(2) (TXA(2)) participates in platelet aggregation and tissue inflammation. In this study, the CXCL1/8 chemokine and TXA(2)-TP receptor expression in the CRSsNP...

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Detalles Bibliográficos
Autores principales: Tsai, Yih-Jeng, Hao, Sheng-Po, Chen, Chih-Li, Wu, Wen-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924833/
https://www.ncbi.nlm.nih.gov/pubmed/27351369
http://dx.doi.org/10.1371/journal.pone.0158438

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