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The Effect of Sitagliptin on Carotid Artery Atherosclerosis in Type 2 Diabetes: The PROLOGUE Randomized Controlled Trial

BACKGROUND: Experimental studies have suggested that dipeptidyl peptidase-4 (DPP-4) inhibitors provide cardiovascular protective effects. We performed a randomized study to evaluate the effects of sitagliptin added on to the conventional therapy compared with conventional therapy alone (diet, exerci...

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Detalles Bibliográficos
Autores principales: Oyama, Jun-ichi, Murohara, Toyoaki, Kitakaze, Masafumi, Ishizu, Tomoko, Sato, Yasunori, Kitagawa, Kazuo, Kamiya, Haruo, Ajioka, Masayoshi, Ishihara, Masaharu, Dai, Kazuoki, Nanasato, Mamoru, Sata, Masataka, Maemura, Koji, Tomiyama, Hirofumi, Higashi, Yukihito, Kaku, Kohei, Yamada, Hirotsugu, Matsuhisa, Munehide, Yamashita, Kentaro, Bando, Yasuko K., Kashihara, Naoki, Ueda, Shinichiro, Inoue, Teruo, Tanaka, Atsushi, Node, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924847/
https://www.ncbi.nlm.nih.gov/pubmed/27351380
http://dx.doi.org/10.1371/journal.pmed.1002051