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Tuning the ion selectivity of glutamate transporter–associated uncoupled conductances
The concentration of glutamate within a glutamatergic synapse is tightly regulated by excitatory amino acid transporters (EAATs). In addition to their primary role in clearing extracellular glutamate, the EAATs also possess a thermodynamically uncoupled Cl(−) conductance. This conductance is activat...
Autores principales: | Cater, Rosemary J., Vandenberg, Robert J., Ryan, Renae M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924932/ https://www.ncbi.nlm.nih.gov/pubmed/27296367 http://dx.doi.org/10.1085/jgp.201511556 |
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