EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells

Glioblastomas (GBM) are aggressive and therapy-resistant brain tumours, which contain a subpopulation of tumour-propagating glioblastoma stem-like cells (GSC) thought to drive progression and recurrence. Diffuse invasion of the brain parenchyma, including along preexisting blood vessels, is a leadin...

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Detalles Bibliográficos
Autores principales: Krusche, Benjamin, Ottone, Cristina, Clements, Melanie P, Johnstone, Ewan R, Goetsch, Katrin, Lieven, Huang, Mota, Silvia G, Singh, Poonam, Khadayate, Sanjay, Ashraf, Azhaar, Davies, Timothy, Pollard, Steven M, De Paola, Vincenzo, Roncaroli, Federico, Martinez-Torrecuadrada, Jorge, Bertone, Paul, Parrinello, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924994/
https://www.ncbi.nlm.nih.gov/pubmed/27350048
http://dx.doi.org/10.7554/eLife.14845

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