Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset

Type 1 diabetes (T1D) is an autoimmune disease that is triggered by both genetic and environmental factors, resulting in the destruction of pancreatic β cells. The disruption of the intestinal epithelial barrier and consequent escape of microbial products may be one of these environmental triggers....

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Detalles Bibliográficos
Autores principales: Costa, Frederico R.C., Françozo, Marcela C.S., de Oliveira, Gabriela G., Ignacio, Aline, Castoldi, Angela, Zamboni, Dario S., Ramos, Simone G., Câmara, Niels O., de Zoete, Marcel R., Palm, Noah W., Flavell, Richard A., Silva, João S., Carlos, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925011/
https://www.ncbi.nlm.nih.gov/pubmed/27325889
http://dx.doi.org/10.1084/jem.20150744

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