Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation

The import of acetyl-CoA into the lumen of the endoplasmic reticulum (ER) by AT-1/SLC33A1 regulates Nε-lysine acetylation of ER-resident and -transiting proteins. Specifically, lysine acetylation within the ER appears to influence the efficiency of the secretory pathway by affecting ER-mediated qual...

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Detalles Bibliográficos
Autores principales: Hullinger, Rikki, Li, Mi, Wang, Jingxin, Peng, Yajing, Dowell, James A., Bomba-Warczak, Ewa, Mitchell, Heather A., Burger, Corinna, Chapman, Edwin R., Denu, John M., Li, Lingjun, Puglielli, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925020/
https://www.ncbi.nlm.nih.gov/pubmed/27242167
http://dx.doi.org/10.1084/jem.20151776

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