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Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development

E2A is an essential regulator of early B cell development. Here, we have demonstrated that E2A together with E2-2 controlled germinal center (GC) B cell and plasma cell development. As shown by the identification of regulated E2A,E2-2 target genes in activated B cells, these E-proteins directly acti...

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Detalles Bibliográficos
Autores principales: Wöhner, Miriam, Tagoh, Hiromi, Bilic, Ivan, Jaritz, Markus, Poliakova, Daniela Kostanova, Fischer, Maria, Busslinger, Meinrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925024/
https://www.ncbi.nlm.nih.gov/pubmed/27261530
http://dx.doi.org/10.1084/jem.20152002