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Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development
E2A is an essential regulator of early B cell development. Here, we have demonstrated that E2A together with E2-2 controlled germinal center (GC) B cell and plasma cell development. As shown by the identification of regulated E2A,E2-2 target genes in activated B cells, these E-proteins directly acti...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925024/ https://www.ncbi.nlm.nih.gov/pubmed/27261530 http://dx.doi.org/10.1084/jem.20152002 |