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GDF-15 enhances intracellular Ca(2+) by increasing Ca(v)1.3 expression in rat cerebellar granule neurons

GDF-15 (growth/differentiation factor 15) is a novel member of the TGF (transforming growth factor)-β superfamily that has critical roles in the central and peripheral nervous systems. We reported previously that GDF-15 increased delayed rectifier outward K(+) currents and K(v)2.1 α subunit expressi...

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Detalles Bibliográficos
Autores principales: Lu, Jun-Mei, Wang, Chang-Ying, Hu, Changlong, Fang, Yan-Jia, Mei, Yan-Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925162/
https://www.ncbi.nlm.nih.gov/pubmed/27114559
http://dx.doi.org/10.1042/BCJ20160362