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PTEN loss and chromosome 8 alterations in Gleason grade 3 prostate cancer cores predicts the presence of un-sampled grade 4 tumor: implications for Active Surveillance

Men who enter active surveillance because their biopsy exhibits only Gleason grade 3 (G3) frequently have higher grade tumor missed by biopsy. Thus, biomarkers are needed that, when measured on G3 tissue, can predict the presence of higher grade tumor in the whole prostate. We evaluated whether PTEN...

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Detalles Bibliográficos
Autores principales:	Trock, Bruce J., Fedor, Helen, Gurel, Bora, Jenkins, Robert B., Knudsen, BS, Fine, Samson W., Said, Jonathan W., Carter, H. Ballentine, Lotan, Tamara L., De Marzo, Angelo M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925272/ https://www.ncbi.nlm.nih.gov/pubmed/27080984 http://dx.doi.org/10.1038/modpathol.2016.63

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