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Occupancy of pramipexole (Sifrol) at cerebral dopamine D2/3 receptors in Parkinson's disease patients

Whereas positron emission tomography (PET) with the antagonist ligand [(18)F]fallypride reveals the composite of dopamine D2 and D3 receptors in brain, treatment of Parkinson's disease (PD) patients with the D3-prefering agonist pramipexole should result in preferential occupancy in the nucleus...

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Detalles Bibliográficos
Autores principales: Deutschländer, Angela, la Fougère, Christian, Boetzel, Kai, Albert, Nathalie L., Gildehaus, Franz-Josef, Bartenstein, Peter, Xiong, Guoming, Cumming, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925448/
https://www.ncbi.nlm.nih.gov/pubmed/27408789
http://dx.doi.org/10.1016/j.nicl.2016.06.007