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Calculating the mean time to capture for tethered ligands and its effect on the chemical equilibrium of bound ligand pairs
We present here the calculation of the mean time to capture of a tethered ligand to the receptor. This calculation is then used to determine the shift in the partitioning between (1) free, (2) singly bound, and (3) doubly bound ligands in chemical equilibrium as a function of the length of the tethe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925454/ https://www.ncbi.nlm.nih.gov/pubmed/27408925 http://dx.doi.org/10.1016/j.dib.2016.05.050 |