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In vivo skin dose measurement in breast conformal radiotherapy

AIM OF THE STUDY: Accurate skin dose assessment is necessary during breast radiotherapy to assure that the skin dose is below the tolerance level and is sufficient to prevent tumour recurrence. The aim of the current study is to measure the skin dose and to evaluate the geometrical/anatomical parame...

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Autores principales: Soleymanifard, Shokouhozaman, Aledavood, Seyed Amir, Noghreiyan, Atefeh Vejdani, Ghorbani, Mahdi, Jamali, Farideh, Davenport, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925725/
https://www.ncbi.nlm.nih.gov/pubmed/27358592
http://dx.doi.org/10.5114/wo.2015.54396
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author Soleymanifard, Shokouhozaman
Aledavood, Seyed Amir
Noghreiyan, Atefeh Vejdani
Ghorbani, Mahdi
Jamali, Farideh
Davenport, David
author_facet Soleymanifard, Shokouhozaman
Aledavood, Seyed Amir
Noghreiyan, Atefeh Vejdani
Ghorbani, Mahdi
Jamali, Farideh
Davenport, David
author_sort Soleymanifard, Shokouhozaman
collection PubMed
description AIM OF THE STUDY: Accurate skin dose assessment is necessary during breast radiotherapy to assure that the skin dose is below the tolerance level and is sufficient to prevent tumour recurrence. The aim of the current study is to measure the skin dose and to evaluate the geometrical/anatomical parameters that affect it. MATERIAL AND METHODS: Forty patients were simulated by TIGRT treatment planning system and treated with two tangential fields of 6 MV photon beam. Wedge filters were used to homogenise dose distribution for 11 patients. Skin dose was measured by thermoluminescent dosimeters (TLD-100) and the effects of beam incident angle, thickness of irradiated region, and beam entry separation on the skin dose were analysed. RESULTS: Average skin dose in treatment course of 50 Gy to the clinical target volume (CTV) was 36.65 Gy. The corresponding dose values for patients who were treated with and without wedge filter were 35.65 and 37.20 Gy, respectively. It was determined that the beam angle affected the average skin dose while the thickness of the irradiated region and the beam entry separation did not affect dose. Since the skin dose measured in this study was lower than the amount required to prevent tumour recurrence, application of bolus material in part of the treatment course is suggested for post-mastectomy advanced breast radiotherapy. It is more important when wedge filters are applied to homogenize dose distribution.
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spelling pubmed-49257252016-06-29 In vivo skin dose measurement in breast conformal radiotherapy Soleymanifard, Shokouhozaman Aledavood, Seyed Amir Noghreiyan, Atefeh Vejdani Ghorbani, Mahdi Jamali, Farideh Davenport, David Contemp Oncol (Pozn) Original Paper AIM OF THE STUDY: Accurate skin dose assessment is necessary during breast radiotherapy to assure that the skin dose is below the tolerance level and is sufficient to prevent tumour recurrence. The aim of the current study is to measure the skin dose and to evaluate the geometrical/anatomical parameters that affect it. MATERIAL AND METHODS: Forty patients were simulated by TIGRT treatment planning system and treated with two tangential fields of 6 MV photon beam. Wedge filters were used to homogenise dose distribution for 11 patients. Skin dose was measured by thermoluminescent dosimeters (TLD-100) and the effects of beam incident angle, thickness of irradiated region, and beam entry separation on the skin dose were analysed. RESULTS: Average skin dose in treatment course of 50 Gy to the clinical target volume (CTV) was 36.65 Gy. The corresponding dose values for patients who were treated with and without wedge filter were 35.65 and 37.20 Gy, respectively. It was determined that the beam angle affected the average skin dose while the thickness of the irradiated region and the beam entry separation did not affect dose. Since the skin dose measured in this study was lower than the amount required to prevent tumour recurrence, application of bolus material in part of the treatment course is suggested for post-mastectomy advanced breast radiotherapy. It is more important when wedge filters are applied to homogenize dose distribution. Termedia Publishing House 2016-02-10 2016 /pmc/articles/PMC4925725/ /pubmed/27358592 http://dx.doi.org/10.5114/wo.2015.54396 Text en Copyright © 2016 Termedia http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Soleymanifard, Shokouhozaman
Aledavood, Seyed Amir
Noghreiyan, Atefeh Vejdani
Ghorbani, Mahdi
Jamali, Farideh
Davenport, David
In vivo skin dose measurement in breast conformal radiotherapy
title In vivo skin dose measurement in breast conformal radiotherapy
title_full In vivo skin dose measurement in breast conformal radiotherapy
title_fullStr In vivo skin dose measurement in breast conformal radiotherapy
title_full_unstemmed In vivo skin dose measurement in breast conformal radiotherapy
title_short In vivo skin dose measurement in breast conformal radiotherapy
title_sort in vivo skin dose measurement in breast conformal radiotherapy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925725/
https://www.ncbi.nlm.nih.gov/pubmed/27358592
http://dx.doi.org/10.5114/wo.2015.54396
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