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Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells()
Despite the tremendous advances in the treatment of childhood solid tumors, rhabdomyosarcoma (RMS) continues to provide a therapeutic challenge. Children with metastatic or relapsed disease have a disease-free survival rate under 30%. Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that...
Autores principales: | Waters, Alicia M., Stafman, Laura L., Garner, Evan F., Mruthyunjayappa, Smitha, Stewart, Jerry E., Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925808/ https://www.ncbi.nlm.nih.gov/pubmed/27567948 http://dx.doi.org/10.1016/j.tranon.2016.06.001 |
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