Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice

5XFAD is an early-onset mouse transgenic model of Alzheimer disease (AD). Up to now there are no studies that focus on the epigenetic changes produced as a result of Aβ-42 accumulation and the possible involvement in the different expression of related AD-genes. Under several behavioral and cognitio...

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Detalles Bibliográficos
Autores principales: Griñán-Ferré, Christian, Sarroca, Sara, Ivanova, Aleksandra, Puigoriol-Illamola, Dolors, Aguado, Fernando, Camins, Antoni, Sanfeliu, Coral, Pallàs, Mercè
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925821/
https://www.ncbi.nlm.nih.gov/pubmed/27013617
http://dx.doi.org/10.18632/aging.100906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925821/
https://www.ncbi.nlm.nih.gov/pubmed/27013617
http://dx.doi.org/10.18632/aging.100906

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