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Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice
5XFAD is an early-onset mouse transgenic model of Alzheimer disease (AD). Up to now there are no studies that focus on the epigenetic changes produced as a result of Aβ-42 accumulation and the possible involvement in the different expression of related AD-genes. Under several behavioral and cognitio...
Autores principales: | Griñán-Ferré, Christian, Sarroca, Sara, Ivanova, Aleksandra, Puigoriol-Illamola, Dolors, Aguado, Fernando, Camins, Antoni, Sanfeliu, Coral, Pallàs, Mercè |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925821/ https://www.ncbi.nlm.nih.gov/pubmed/27013617 http://dx.doi.org/10.18632/aging.100906 |
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