N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice

Genetic factors combined with oxidative stress are major determinants of age-related hearing loss (ARHL), one of the most prevalent disorders of the elderly. Dwarf grey mice, Ggt1(dwg/dwg), are homozygous for a loss of function mutation of the γ-glutamyl transferase 1 gene, which encodes an importan...

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Detalles Bibliográficos
Autores principales: Ding, Dalian, Jiang, Haiyan, Chen, Guang-Di, Longo-Guess, Chantal, Muthaiah, Vijaya Prakash Krishnan, Tian, Cong, Sheppard, Adam, Salvi, Richard, Johnson, Kenneth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925825/
https://www.ncbi.nlm.nih.gov/pubmed/26977590
http://dx.doi.org/10.18632/aging.100927

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