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Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats
Rapamycin is known to extend lifespan. We conducted a randomized placebo-controlled study of enteric rapamycin-treatment to evaluate its effect on physical function in old low capacity runner (LCR) rats, a rat model selected from diverse genetic background for low intrinsic aerobic exercise capacity...
Autores principales: | Xue, Qian-Li, Yang, Huanle, Li, Hui-Fen, Abadir, Peter M., Burks, Tyesha N., Koch, Lauren G., Britton, Steven L., Carlson, Joshua, Chen, Laura, Walston, Jeremy D., Leng, Sean X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925827/ https://www.ncbi.nlm.nih.gov/pubmed/26997106 http://dx.doi.org/10.18632/aging.100929 |
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