Platelet Activation: The Mechanisms and Potential Biomarkers

Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent...

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Detalles Bibliográficos
Autores principales: Yun, Seong-Hoon, Sim, Eun-Hye, Goh, Ri-Young, Park, Joo-In, Han, Jin-Yeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925965/
https://www.ncbi.nlm.nih.gov/pubmed/27403440
http://dx.doi.org/10.1155/2016/9060143
Descripción
Sumario:Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent years. In this review, we discuss recent advances in the pathways of platelet activation and potential application of platelet activation biomarkers to diagnosis and prediction of disease states.

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