Platelet Activation: The Mechanisms and Potential Biomarkers

Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent...

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Detalles Bibliográficos
Autores principales: Yun, Seong-Hoon, Sim, Eun-Hye, Goh, Ri-Young, Park, Joo-In, Han, Jin-Yeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925965/
https://www.ncbi.nlm.nih.gov/pubmed/27403440
http://dx.doi.org/10.1155/2016/9060143
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author Yun, Seong-Hoon
Sim, Eun-Hye
Goh, Ri-Young
Park, Joo-In
Han, Jin-Yeong
author_facet Yun, Seong-Hoon
Sim, Eun-Hye
Goh, Ri-Young
Park, Joo-In
Han, Jin-Yeong
author_sort Yun, Seong-Hoon
collection PubMed
description Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent years. In this review, we discuss recent advances in the pathways of platelet activation and potential application of platelet activation biomarkers to diagnosis and prediction of disease states.
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spelling pubmed-49259652016-07-11 Platelet Activation: The Mechanisms and Potential Biomarkers Yun, Seong-Hoon Sim, Eun-Hye Goh, Ri-Young Park, Joo-In Han, Jin-Yeong Biomed Res Int Review Article Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent years. In this review, we discuss recent advances in the pathways of platelet activation and potential application of platelet activation biomarkers to diagnosis and prediction of disease states. Hindawi Publishing Corporation 2016 2016-06-15 /pmc/articles/PMC4925965/ /pubmed/27403440 http://dx.doi.org/10.1155/2016/9060143 Text en Copyright © 2016 Seong-Hoon Yun et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Yun, Seong-Hoon
Sim, Eun-Hye
Goh, Ri-Young
Park, Joo-In
Han, Jin-Yeong
Platelet Activation: The Mechanisms and Potential Biomarkers
title Platelet Activation: The Mechanisms and Potential Biomarkers
title_full Platelet Activation: The Mechanisms and Potential Biomarkers
title_fullStr Platelet Activation: The Mechanisms and Potential Biomarkers
title_full_unstemmed Platelet Activation: The Mechanisms and Potential Biomarkers
title_short Platelet Activation: The Mechanisms and Potential Biomarkers
title_sort platelet activation: the mechanisms and potential biomarkers
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925965/
https://www.ncbi.nlm.nih.gov/pubmed/27403440
http://dx.doi.org/10.1155/2016/9060143
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