Nod2-Nodosome in a Cell-Free System: Implications in Pathogenesis and Drug Discovery for Blau Syndrome and Early-Onset Sarcoidosis

Nucleotide-binding oligomerization domain-containing protein (Nod) 2 is an intracellular pattern recognition receptor, which recognizes muramyl dipeptide (N-Acetylmuramyl-L-Alanyl-D-Isoglutamine: MDP), a bacterial peptidoglycan component, and makes a NF-κB-activating complex called nodosome with ada...

Descripción completa

Detalles Bibliográficos
Autores principales: Iwasaki, Tomoyuki, Kaneko, Naoe, Ito, Yuki, Takeda, Hiroyuki, Sawasaki, Tatsuya, Heike, Toshio, Migita, Kiyoshi, Agematsu, Kazunaga, Kawakami, Atsushi, Morikawa, Shinnosuke, Mokuda, Sho, Kurata, Mie, Masumoto, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926014/
https://www.ncbi.nlm.nih.gov/pubmed/27403452
http://dx.doi.org/10.1155/2016/2597376

Ejemplares similares

Ejemplares similares