MRA_1571 is required for isoleucine biosynthesis and improves Mycobacterium tuberculosis H37Ra survival under stress

Threonine dehydratase is a pyridoxal 5-phosphate dependent enzyme required for isoleucine biosynthesis. Threonine dehydratase (IlvA) participates in conversion of threonine to 2-oxobutanoate and ammonia is released as a by-product. MRA_1571 is annotated to be coding for IlvA in Mycobacterium tubercu...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Rishabh, Keshari, Deepa, Singh, Kumar Sachin, Yadav, Shailendra, Singh, Sudheer Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926081/
https://www.ncbi.nlm.nih.gov/pubmed/27353854
http://dx.doi.org/10.1038/srep27997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926081/
https://www.ncbi.nlm.nih.gov/pubmed/27353854
http://dx.doi.org/10.1038/srep27997

Ejemplares similares