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Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels

Growth differentiation factor-15 (GDF-15) has been implicated in ischemic brain injury and synapse development, but its involvement in modulating neuronal excitability and synaptic transmission remain poorly understood. In this study, we investigated the effects of GDF-15 on non-evoked miniature exc...

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Detalles Bibliográficos
Autores principales: Liu, Dong-Dong, Lu, Jun-Mei, Zhao, Qian-Ru, Hu, Changlong, Mei, Yan-Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926092/
https://www.ncbi.nlm.nih.gov/pubmed/27353765
http://dx.doi.org/10.1038/srep28653