Cargando…

Anti-Human Endoglin (hCD105) Immunotoxin—Containing Recombinant Single Chain Ribosome-Inactivating Protein Musarmin 1

Endoglin (CD105) is an accessory component of the TGF-β receptor complex, which is expressed in a number of tissues and over-expressed in the endothelial cells of tumor neovasculature. Targeting endoglin with immunotoxins containing type 2 ribosome-inactivating proteins has proved an effective tool...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barriuso, Begoña, Antolín, Pilar, Arias, F. Javier, Girotti, Alessandra, Jiménez, Pilar, Cordoba-Diaz, Manuel, Cordoba-Diaz, Damián, Girbés, Tomás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926150/ https://www.ncbi.nlm.nih.gov/pubmed/27294959 http://dx.doi.org/10.3390/toxins8060184

Ejemplares similares

Elderberries: A Source of Ribosome-Inactivating Proteins with Lectin Activity
por: Tejero, Jesús, et al.
Publicado: (2015)

Use of Ribosome-Inactivating Proteins from Sambucus for the Construction of Immunotoxins and Conjugates for Cancer Therapy
por: Ferreras, José M., et al.
Publicado: (2011)

Lectin Digestibility and Stability of Elderberry Antioxidants to Heat Treatment In Vitro
por: Jiménez, Pilar, et al.
Publicado: (2017)

Toxicity of the Anti-ribosomal Lectin Ebulin f in Lungs and Intestines in Elderly Mice
por: Garrosa, Manuel, et al.
Publicado: (2015)

5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
por: Lund, Kaja, et al.
Publicado: (2017)

Endotoxins from a Pharmacopoeial Point of View
por: Franco, Elvira, et al.
Publicado: (2018)

Expression of endoglin (CD105) in cervical cancer
por: Zijlmans, H J, et al.
Publicado: (2009)

Unexpected Toxicity of Green Tea Polyphenols in Combination with the Sambucus RIL Ebulin
por: Rojo, M. Ángeles, et al.
Publicado: (2020)

Evaluation of Endoglin (CD105) expression in pediatric rhabdomyosarcoma
por: Di Paolo, Virginia, et al.
Publicado: (2018)

CD105 (Endoglin) as negative prognostic factor in AML
por: Kauer, Joseph, et al.
Publicado: (2019)

Isolation and Molecular Characterization of Two Lectins from Dwarf Elder (Sambucus ebulus L.) Blossoms Related to the Sam n1 Allergen
por: Jimenez, Pilar, et al.
Publicado: (2013)

Continuous endoglin (CD105) overexpression disrupts angiogenesis and facilitates tumor cell metastasis
por: Ollauri-Ibáñez, Claudia, et al.
Publicado: (2020)

Identification of CD105 (endoglin) as novel risk marker in CLL
por: Greiner, Sarah M., et al.
Publicado: (2022)

Study of expression of endoglin (CD105) in oral squamous cell carcinoma
por: Mahapatra, Niva, et al.
Publicado: (2021)

Immunotoxins Constructed with Ribosome-Inactivating Proteins and their Enhancers: A Lethal Cocktail with Tumor Specific Efficacy
por: Gilabert-Oriol, Roger, et al.
Publicado: (2014)

The Use of Plant-Derived Ribosome Inactivating Proteins in Immunotoxin Development: Past, Present and Future Generations
por: Rust, Aleksander, et al.
Publicado: (2017)

Ebulin from Dwarf Elder (Sambucus ebulus L.): A Mini-Review
por: Jiménez, Pilar, et al.
Publicado: (2015)

A novel recombinant immunotoxin with the smallest ribosome-inactivating protein Luffin P1: T-cell cytotoxicity and prolongation of allograft survival
por: Wang, Rupeng, et al.
Publicado: (2010)

Role of Endoglin (CD105) in the Progression of Hepatocellular Carcinoma and Anti-Angiogenic Therapy
por: Kasprzak, Aldona, et al.
Publicado: (2018)

Endoglin (CD105) and VEGF as potential angiogenic and dissemination markers for colorectal cancer
por: Nogués, Ana, et al.
Publicado: (2020)

Particular distribution and expression pattern of endoglin (CD105) in the liver of patients with hepatocellular carcinoma
por: Yu, Decai, et al.
Publicado: (2007)

Endoglin (CD105) expression in ovarian serous carcinoma effusions is related to chemotherapy status
por: Bock, Annika J., et al.
Publicado: (2011)

ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours
por: Gromova, Petra, et al.
Publicado: (2012)

Hot and Cold Tumors: Is Endoglin (CD105) a Potential Target for Vessel Normalization?
por: Ollauri-Ibáñez, Claudia, et al.
Publicado: (2021)

Endoglin/CD105-Based Imaging of Cancer and Cardiovascular Diseases: A Systematic Review
por: Sier, Vincent Q., et al.
Publicado: (2021)

Horoscopic role of CD105 (Endoglin) in progression of oral lichen planus: An immunohistochemical study
por: Parvathala, Poornima, et al.
Publicado: (2021)

Endoglin (CD105) and proliferation index in recurrent glioblastoma treated with anti-angiogenic therapy
por: Bastos, António G. P., et al.
Publicado: (2022)

Highlights on endoglin (CD105): from basic findings towards clinical applications in human cancer
por: Fonsatti, Ester, et al.
Publicado: (2004)

PROGNOSTIC ROLE OF CD44 EXPRESSION AND NEOVASCULARIZATION DETERMINED BY ENDOGLIN (CD105) IN GLIOBLASTOMA PATIENTS
por: Mihić, Josip, et al.
Publicado: (2019)

Endoglin (CD105) as a putative prognostic biomarker for colorectal cancer: a systematic review
por: Sur, Daniel, et al.
Publicado: (2022)

Endoglin in the Spotlight to Treat Cancer
por: González Muñoz, Teresa, et al.
Publicado: (2021)

Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin
por: Walker, Douglas G., et al.
Publicado: (2019)

Selective cytotoxic activity of immunotoxins composed of a monoclonal anti-Thy 1.1 antibody and the ribosome-inactivating proteins bryodin and momordin.
por: Stirpe, F., et al.
Publicado: (1988)

Modulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer
por: Liu, Yingmiao, et al.
Publicado: (2014)

Gamma heavy chain disease (γ-HCD) as iatrogenic immunodeficiency- associated lymphoproliferative disorder: Possible emergent subtype of rheumatoid arthritis-associated γ-HCD
por: Tsunemine, Hiroko, et al.
Publicado: (2019)

CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma
por: Smith, Stuart J., et al.
Publicado: (2012)

Endoglin (CD105) is a more appropriate marker than CD31 for detecting microvessels in carotid artery plaques
por: Fukumitsu, Ryu, et al.
Publicado: (2013)

Endoglin (CD105) expression differentiates between aseptic loosening and periprosthetic joint infection after total joint arthroplasty
por: Jansen, Philipp, et al.
Publicado: (2014)

A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors
por: Listik, Eduardo, et al.
Publicado: (2021)

Endoglin inhibitor TRC105 with or without bevacizumab for bevacizumab-refractory glioblastoma (ENDOT): a multicenter phase II trial
por: Ahluwalia, Manmeet S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lbheidhkhtsc6qav165g81th51