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Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza Hemagglutinin
Influenza genes evolve mostly via point mutations, and so knowing the effect of every amino-acid mutation provides information about evolutionary paths available to the virus. We and others have combined high-throughput mutagenesis with deep sequencing to estimate the effects of large numbers of mut...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926175/ https://www.ncbi.nlm.nih.gov/pubmed/27271655 http://dx.doi.org/10.3390/v8060155 |