Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia

BACKGROUND: Altered metabolism is a hallmark of cancer. However, the role of genomic changes in metabolic genes driving the tumour metabolic shift remains to be elucidated. Here, we have investigated the genomic and transcriptomic changes underlying this shift across ten different cancer types. RESU...

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Detalles Bibliográficos
Autores principales: Haider, Syed, McIntyre, Alan, van Stiphout, Ruud G. P. M., Winchester, Laura M., Wigfield, Simon, Harris, Adrian L., Buffa, Francesca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926297/
https://www.ncbi.nlm.nih.gov/pubmed/27358048
http://dx.doi.org/10.1186/s13059-016-0999-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926297/
https://www.ncbi.nlm.nih.gov/pubmed/27358048
http://dx.doi.org/10.1186/s13059-016-0999-8

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