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Targeted Gene Knockin in Porcine Somatic Cells Using CRISPR/Cas Ribonucleoproteins
The pig is an ideal large animal model for genetic engineering applications. A relatively short gestation interval and large litter size makes the pig a conducive model for generating and propagating genetic modifications. The domestic pig also shares close similarity in anatomy, physiology, size, a...
Autores principales: | Park, Ki-Eun, Park, Chi-Hun, Powell, Anne, Martin, Jessica, Donovan, David M., Telugu, Bhanu P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926344/ https://www.ncbi.nlm.nih.gov/pubmed/27240344 http://dx.doi.org/10.3390/ijms17060810 |
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