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Crystal Structure of Cytochrome P450 (CYP105P2) from Streptomyces peucetius and Its Conformational Changes in Response to Substrate Binding

Cytochrome P450 monooxygenases (CYP, EC 1.14.14.1) belong to a large family of enzymes that catalyze the hydroxylation of various substrates. Here, we present the crystal structure of CYP105P2 isolated from Streptomyces peucetius ATCC27952 at a 2.1 Å resolution. The structure shows the presence of a...

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Detalles Bibliográficos
Autores principales: Lee, Chang Woo, Lee, Joo-Ho, Rimal, Hemraj, Park, Hyun, Lee, Jun Hyuck, Oh, Tae-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926347/
https://www.ncbi.nlm.nih.gov/pubmed/27231902
http://dx.doi.org/10.3390/ijms17060813