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All-Trans Retinoic Acid Modulates DNA Damage Response and the Expression of the VEGF-A and MKI67 Genes in ARPE-19 Cells Subjected to Oxidative Stress

Age-related macular degeneration (AMD) is characterized by the progressive degradation of photoreceptors and retinal pigment epithelium (RPE) cells. ARPE-19 is an RPE cell line established as an in vitro model for the study of AMD pathogenesis. Oxidative stress is an AMD pathogenesis factor that ind...

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Detalles Bibliográficos
Autores principales: Tokarz, Paulina, Piastowska-Ciesielska, Agnieszka Wanda, Kaarniranta, Kai, Blasiak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926432/
https://www.ncbi.nlm.nih.gov/pubmed/27314326
http://dx.doi.org/10.3390/ijms17060898

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