In Silico Prediction of Cytochrome P450-Drug Interaction: QSARs for CYP3A4 and CYP2C9

Cytochromes P450 (CYP) are the main actors in the oxidation of xenobiotics and play a crucial role in drug safety, persistence, bioactivation, and drug-drug/food-drug interaction. This work aims to develop Quantitative Structure-Activity Relationship (QSAR) models to predict the drug interaction wit...

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Detalles Bibliográficos
Autores principales: Nembri, Serena, Grisoni, Francesca, Consonni, Viviana, Todeschini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926447/
https://www.ncbi.nlm.nih.gov/pubmed/27294921
http://dx.doi.org/10.3390/ijms17060914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926447/
https://www.ncbi.nlm.nih.gov/pubmed/27294921
http://dx.doi.org/10.3390/ijms17060914

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