Efficiency of gaseous ozone in reducing the development of dry socket following surgical third molar extraction

OBJECTIVE: The objective of this study was to assess the efficacy of ozone gas (O(3)) on the reduction of dry socket (DS) occurrence following surgical extraction of lower jaw third molars, influence of the indication for the extraction, and the difficulty of extraction on the incidence of DS. MATERIALS AND METHODS: This study included thirty patients with bilaterally impacted third molars of mandible requiring surgical procedure for extraction. Following extraction, in the control group, saline solution was used for irrigation of extraction sockets and in the experimental group, intra-alveolar O(3) was applied for 12 s (Prozone, W and H, UK, Ltd.). The surgeries were performed by the same oral surgeon. The follow-up visits were performed at 48 h and on day seven, postsurgery where the symptoms of DS were evaluated and intensity of pain has been recorded using visual analog scale 0–100. RESULTS: In this pilot study, DS was present in 16.67% and 3.33% of cases in the control and experimental groups, respectively (P = 0.20). CONCLUSION: The application of O(3) may reduce the incidence of DS and accelerates the recovery period after the surgery. Prophylactic use of O(3) may be suggested in all patients, especially in the patients at a risk of development of DS.