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Pathogenesis of myasthenia gravis: update on disease types, models, and mechanisms

Myasthenia gravis is an autoimmune disease of the neuromuscular junction (NMJ) caused by antibodies that attack components of the postsynaptic membrane, impair neuromuscular transmission, and lead to weakness and fatigue of skeletal muscle. This can be generalised or localised to certain muscle grou...

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Detalles Bibliográficos
Autores principales: Phillips, William D., Vincent, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926737/
https://www.ncbi.nlm.nih.gov/pubmed/27408701
http://dx.doi.org/10.12688/f1000research.8206.1