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Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment
According to the multi-step carcinogenesis model of cancer, initiation results in a benign tumor and subsequent genetic alterations lead to tumor progression and the acquisition of the hallmarks of cancer. This article will review recent discoveries in our understanding of initiation and progression...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926755/ https://www.ncbi.nlm.nih.gov/pubmed/27408703 http://dx.doi.org/10.12688/f1000research.8247.1 |
| _version_ | 1782440178113052672 |
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| author | Yeh, Iwei |
| author_facet | Yeh, Iwei |
| author_sort | Yeh, Iwei |
| collection | PubMed |
| description | According to the multi-step carcinogenesis model of cancer, initiation results in a benign tumor and subsequent genetic alterations lead to tumor progression and the acquisition of the hallmarks of cancer. This article will review recent discoveries in our understanding of initiation and progression in melanocytic neoplasia and the impact on diagnostic dermatopathology. |
| format | Online Article Text |
| id | pubmed-4926755 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | F1000Research |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-49267552016-07-11 Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment Yeh, Iwei F1000Res Review According to the multi-step carcinogenesis model of cancer, initiation results in a benign tumor and subsequent genetic alterations lead to tumor progression and the acquisition of the hallmarks of cancer. This article will review recent discoveries in our understanding of initiation and progression in melanocytic neoplasia and the impact on diagnostic dermatopathology. F1000Research 2016-06-28 /pmc/articles/PMC4926755/ /pubmed/27408703 http://dx.doi.org/10.12688/f1000research.8247.1 Text en Copyright: © 2016 Yeh I http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Review Yeh, Iwei Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment |
| title | Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment |
| title_full | Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment |
| title_fullStr | Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment |
| title_full_unstemmed | Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment |
| title_short | Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment |
| title_sort | recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926755/ https://www.ncbi.nlm.nih.gov/pubmed/27408703 http://dx.doi.org/10.12688/f1000research.8247.1 |
| work_keys_str_mv | AT yehiwei recentadvancesinmoleculargeneticsofmelanomaprogressionimplicationsfordiagnosisandtreatment |