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INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

Superenhancers (SEs) are large genomic regions with a high density of enhancer marks. In cancer, SEs are found near oncogenes and dictate cancer gene expression. However, how oncogenic SEs are regulated remains poorly understood. Here, we show that INO80, a chromatin remodeling complex, is required...

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Detalles Bibliográficos
Autores principales:	Zhou, Bingying, Wang, Li, Zhang, Shu, Bennett, Brian D., He, Fan, Zhang, Yan, Xiong, Chengliang, Han, Leng, Diao, Lixia, Li, Pishun, Fargo, David C., Cox, Adrienne D., Hu, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926866/ https://www.ncbi.nlm.nih.gov/pubmed/27340176 http://dx.doi.org/10.1101/gad.277178.115

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