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Haplotype estimation for biobank scale datasets
The UK Biobank (UKB) has recently released genotypes on 152,328 individuals together with extensive phenotypic and lifestyle information. We present a new phasing method SHAPEIT3 that can handle such biobank scale datasets and results in switch error rates as low as ~0.3%. The method exhibits O(Nlog...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926957/ https://www.ncbi.nlm.nih.gov/pubmed/27270105 http://dx.doi.org/10.1038/ng.3583 |