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Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351

BACKGROUND: [(18)F]THK5351, a recently-developed positron emission tomography (PET) tracer for measuring tau neurofibrillary tangle accumulation, may help researchers examine aging, disease, and tau pathology in living human brains. We examined THK5351 tracer pharmacokinetics to define an optimal ac...

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Detalles Bibliográficos
Autores principales:	Lockhart, Samuel N., Baker, Suzanne L., Okamura, Nobuyuki, Furukawa, Katsutoshi, Ishiki, Aiko, Furumoto, Shozo, Tashiro, Manabu, Yanai, Kazuhiko, Arai, Hiroyuki, Kudo, Yukitsuka, Harada, Ryuichi, Tomita, Naoki, Hiraoka, Kotaro, Watanuki, Shoichi, Jagust, William J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927104/ https://www.ncbi.nlm.nih.gov/pubmed/27355840 http://dx.doi.org/10.1371/journal.pone.0158460

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