Loss of CENP-F results in distinct microtubule-related defects without chromosomal abnormalities

Microtubule (MT)-binding centromere protein F (CENP-F) was previously shown to play a role exclusively in chromosome segregation during cellular division. Many cell models of CENP-F depletion show a lag in the cell cycle and aneuploidy. Here, using our novel genetic deletion model, we show that CENP...

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Detalles Bibliográficos
Autores principales: Pfaltzgraff, Elise R., Roth, Gretchen M., Miller, Paul M., Gintzig, Anneelizabeth G., Ohi, Ryoma, Bader, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927273/
https://www.ncbi.nlm.nih.gov/pubmed/27146114
http://dx.doi.org/10.1091/mbc.E15-12-0848

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