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Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae

Caveolin 1 (Cav1) is a required structural component of caveolae, and its phosphorylation by Src is associated with an increase in caveolae-mediated endocytosis. Here we demonstrate, using quantitative live-cell 4D, TIRF, and FRET imaging, that endocytosis and trafficking of caveolae are associated...

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Detalles Bibliográficos
Autores principales: Zimnicka, Adriana M., Husain, Yawer S., Shajahan, Ayesha N., Sverdlov, Maria, Chaga, Oleg, Chen, Zhenlong, Toth, Peter T., Klomp, Jennifer, Karginov, Andrei V., Tiruppathi, Chinnaswamy, Malik, Asrar B., Minshall, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927282/
https://www.ncbi.nlm.nih.gov/pubmed/27170175
http://dx.doi.org/10.1091/mbc.E15-11-0756