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Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae
Caveolin 1 (Cav1) is a required structural component of caveolae, and its phosphorylation by Src is associated with an increase in caveolae-mediated endocytosis. Here we demonstrate, using quantitative live-cell 4D, TIRF, and FRET imaging, that endocytosis and trafficking of caveolae are associated...
Autores principales: | Zimnicka, Adriana M., Husain, Yawer S., Shajahan, Ayesha N., Sverdlov, Maria, Chaga, Oleg, Chen, Zhenlong, Toth, Peter T., Klomp, Jennifer, Karginov, Andrei V., Tiruppathi, Chinnaswamy, Malik, Asrar B., Minshall, Richard D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927282/ https://www.ncbi.nlm.nih.gov/pubmed/27170175 http://dx.doi.org/10.1091/mbc.E15-11-0756 |
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