Quantitative detection of low-abundance somatic structural variants in normal cells by high throughput sequencing

The detection and quantification of low-abundance somatic DNA mutations by high throughput sequencing is challenging because of the difficulty in distinguishing errors from true mutations. While there are several approaches available for analyzing somatic point mutations and small indels, an accurat...

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Detalles Bibliográficos
Autores principales: Quispe-Tintaya, Wilber, Gorbacheva, Tatyana, Lee, Moonsook, Makhortov, Sergei, Popov, Vasily N., Vijg, Jan, Maslov, Alexander Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927357/
https://www.ncbi.nlm.nih.gov/pubmed/27271197
http://dx.doi.org/10.1038/nmeth.3893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927357/
https://www.ncbi.nlm.nih.gov/pubmed/27271197
http://dx.doi.org/10.1038/nmeth.3893

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